CAS: 1575736-03-6

Methyl 4-methylumbelliferyl hexylphosphonate is a hydrophobic molecule that can be used as an additive in a variety of products, including plastics. It can be used to determine the uptake of additives by immobilizing the molecule to various surfaces, such as styrene and multi-walled carbon nanotubes. It can also be used for kinetic studies, such as determining the rate at which styrene is metabolized by lipase. This compound has been used to label DNA with fluorescence techniques and has also been immobilized on mesoporous silica nanoparticles with propionate groups for use as a fluorophore in immunoassays.

Methyl 4-methylumbelliferyl hexyl phosphonate is a lipase suicide inhibitor that is a fluorogenic substrate for lipases which upon enzymatic action, binds irreversibly to the lipase and inactivates it. The substrate can be used for the determination of active sites in lipases and the fluorescent signal can be detected at Ex 363 nm and Em 465 nm.

Lipase suicide inhibitor product with the ability to determine lipase and hydrolase activity in complex protein mixtures. They are suitable for use in active site titration experiments to establish the molar amount of enzyme.