4,5-Diiodo-1H-imidazole is a heterocyclic organic compound characterized by the presence of an imidazole ring substituted with two iodine atoms at the 4 and 5 positions. This compound is notable for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to the biological activity often associated with halogenated imidazoles. The presence of iodine atoms can enhance the lipophilicity and biological interactions of the molecule. 4,5-Diiodo-1H-imidazole is typically a solid at room temperature and may exhibit varying solubility in organic solvents. Its chemical structure allows for participation in various chemical reactions, including nucleophilic substitutions and coupling reactions, making it a versatile intermediate in organic synthesis. Additionally, the compound's properties, such as melting point, boiling point, and reactivity, can be influenced by the presence of the iodine substituents, which can affect the electronic distribution within the imidazole ring. Overall, 4,5-Diiodo-1H-imidazole is of interest in both synthetic and medicinal chemistry contexts.

4,5-Diiodo-1H-imidazole

15813-09-9: 1H-Imidazole, 4,5-diiodo-, 4,5-Diiodo-imidazole, 4,5-Diiodoimidazole, Imidazole, 4,5-diiodo-, , 4,5-Diiodo-1H-imidazole

1H-Imidazole, 4,5-diiodo-

4,5-Diiodo-1H-imidazole is an imidazole derivative that has been shown to have a pesticide effect on marine sponges. This compound reacts with s-adenosylhomocysteine hydrolase and blocks the formation of methylcobalamin. 4,5-Diiodo-1H-imidazole has also been shown to have antibacterial activity against E. coli, Salmonella typhimurium and Staphylococcus aureus. 4,5-Diiodo-1H-imidazole inhibits bacterial growth by inhibiting protein synthesis through inhibition of the enzyme methionine adenosyltransferase (MAT). The reaction rate is influenced by functional groups present in the molecule and by tautomers that exist between different forms of the compound.

CAS 15813-09-9: 4,5-Diiodo-1H-imidazole

1H-Imidazole, 4,5-diiodo-

Ref: IN-DA001Q0E

4,5-Diiodo-1H-imidazole

Ref: 54-OR10450

4,5-Diiodo-1H-imidazole

Ref: 3D-FD147395

4,5-Diiodo-1H-imidazole

Ref: 10-F067398