CAS 15827-10-8: Propanoic acid, 2,2-dimethyl-, zinc salt (2:1)

Zinc pivalate is an organic compound that has a carboxyl group at one end and an aminoglycoside group at the other. The molecule's functional groups include a proton, alcohol group, formyl group, and amine. It can be used to treat bacterial infections. Zinc pivalate has been shown to inhibit bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Zinc pivalate also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Zinc(Ii) Pivalate

Zinc pivalate is a coordination complex that has been shown to be an effective metal-based catalyst for amine-mediated cross-coupling reactions. It has also been used as a ligand in the synthesis of metal complexes. Zinc pivalate is soluble in water and its molecular weight is 198.2 daltons. It has two functional groups, carboxylate and formyl group, and can be synthesized by reacting zinc chloride with pivalic acid. The molecule contains a water molecule that acts as a base to deprotonate the carboxylate group on the zinc atom, forming an alcohol group which reacts with amines to produce an aminoglycoside. Zinc pivalate is also capable of forming coordination complexes with palladium, which catalyzes cross-coupling reactions with chlorides under mild conditions.