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CAS 158440-71-2: (-)-Irofulven

Formula:C15H18O3
InChI:InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1
InChI key:InChIKey=NICJCIQSJJKZAH-AWEZNQCLSA-N
SMILES:CC=1C2([C@@](C)(O)C(=O)C=3C1C(CO)=C(C)C3)CC2
Synonyms:
  • (-)-(Hydroxymethyl)acylfulvene
  • (6'R)-6'-hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-inden]-7'(6'H)-one
  • (6′R)-6′-Hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethylspiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one
  • 6-Hmaf
  • Hmaf
  • Hydroxymethylacylfulvene
  • Irofulven
  • Mgi-114
  • Nsc-683863
  • Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 6′-hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethyl-, (6′R)-
  • Spiro[cyclopropane-1,5′-[5H]inden]-7′(6′H)-one, 6′-hydroxy-3′-(hydroxymethyl)-2′,4′,6′-trimethyl-, (R)-
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Found 5 products.
  • (-)-Irofulven
    Targetmol
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    (-)-Irofulven

    CAS:
    Irofulven is an agent of DNA-damaging and antitumor. It is used for the treatment of advanced solid tumors, including prostate, ovarian, and pancreatic cancers.
    Formula:C15H18O3
    Color and Shape:Solid
    Molecular weight:246.30

    Ref: TM-T24176

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  • (R)-Irofulven
    Biosynth
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    (R)-Irofulven

    CAS:
    (R)-Irofulven is a cytotoxic agent that acts by inhibiting the mitochondrial membrane potential. It has been shown to have high potency against carcinoma cell lines and has been used in toxicity studies. (R)-Irofulven is also effective against high-resistant cells, such as intramolecular hydrogen. This drug induces caspase-independent cell death and chemical stability, which makes it a good candidate for use in children. The concentration-time curve of (R)-Irofulven shows that this drug kills cancer cells at low concentrations and has a long elimination half-life, making it an ideal candidate for cancer treatment.
    Formula:C15H18O3
    Purity:Min. 95%
    Molecular weight:246.3 g/mol

    Ref: 3D-FI24650

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  • (R)-Irofulven
    TLC
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    (R)-Irofulven

    CAS:
    Formula:C15H18O3
    Molecular weight:246.31

    Ref: 4Z-I-151001

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  • (R)-Irofulven
    TRC
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    (R)-Irofulven

    Controlled Product
    CAS:
    Applications Semi-synrhetic antitumor agent derived from Illudin S. Inhibits DNA synthesis and induces apoptosis in tumor cells. Antineoplastic. References Woynarowski, J.M., et al.: Biochem. Pharmacol., 54, 1181 (1997), Alexandre, J., et al.: Clin. Cancer Res., 10, 3377 (2004), Senzer, N., et al.: Am. J. Clin. Oncol., 28, 36 (2005),
    Formula:C15H18O3
    Color and Shape:Neat
    Molecular weight:246.31

    Ref: TR-I769500

    25mg
    17,220.00€
  • Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 6'-hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethyl-,…
    Indagoo
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    Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 6'-hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethyl-, (6'R)-

    CAS:
    Formula:C15H18O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:246.30162000000004

    Ref: IN-DA001Q6R

    1mg
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