Trans-N,N-Dimethylamino-2-cyclohexanol is an organic compound characterized by its cyclic structure and the presence of a dimethylamino group. It features a cyclohexanol backbone, which contributes to its potential as a chiral molecule, influencing its interactions in biological systems. The compound is typically a colorless to pale yellow liquid and is soluble in polar solvents due to the hydroxyl group, which can engage in hydrogen bonding. Its dimethylamino group imparts basic properties, allowing it to participate in various chemical reactions, including nucleophilic substitutions and protonation. The trans configuration of the dimethylamino group relative to the hydroxyl group is significant, as it can affect the compound's steric and electronic properties, influencing its reactivity and biological activity. This compound may be of interest in medicinal chemistry and pharmacology, particularly in the development of drugs targeting the central nervous system, due to its potential to cross the blood-brain barrier. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

trans-N,N-Dimethylamino-2-cyclohexanol

15910-74-4: Cyclohexanol, 2-(dimethylamino)-, trans-, 2-(Dimethylamino)Cyclohexanol, (1R,2R)-2-dimethylaminocyclohexan-1-ol

(1R,2R)-2-(Dimethylamino)cyclohexanol

Cyclohexanol, 2-(dimethylamino)-, (1R,2R)-rel-

2-(Dimethylamino)cyclohexanol is a cocaine analog that has methylamino group. It binds to opioid receptors, and this binding is selective for the δ-opioid receptor. This compound also has a high affinity for ligands with an α-methyl group. 2-(Dimethylamino)cyclohexanol can be methylated to form 2-methylaminocyclohexanol, which has similar properties as the parent compound. The n-oxide of 2-(dimethylamino)cyclohexanol is more potent than the parent compound in binding to opioid receptors and naloxone-reversible effects. Oxidation by periodate produces a cyclohexanone derivative that has affinity for both opioid and dopamine receptors.

CAS 15910-74-4: trans-N,N-Dimethylamino-2-cyclohexanol

(1R,2R)-2-(Dimethylamino)cyclohexanol

Ref: 10-F694890

Cyclohexanol, 2-(dimethylamino)-, (1R,2R)-rel-

Ref: IN-DA001QH1

2-(Dimethylamino)cyclohexanol

Ref: 3D-FD121821