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CAS 159351-69-6: Everolimus

Formula:C53H83NO14
InChI:InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
InChI key:InChIKey=HKVAMNSJSFKALM-GKUWKFKPSA-N
SMILES:O=C1N2[C@](C(=O)O[C@]([C@@H](C[C@H]3C[C@@H](OC)[C@H](OCCO)CC3)C)(CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(/C)\[C@@H](OC)C[C@]4(O[C@@](O)(C1=O)[C@H](C)CC4)[H])[H])(CCCC2)[H]
Synonyms:
  • (3S,6R,7Z,9R,10R,12R,14S,15E,17Z,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv.
  • 40-O-(2-Hydroxyethyl)rapamycin
  • 42-O-(2-Hydroxy)ethyl rapamycin
  • 42-O-(2-Hydroxyethyl)-rapamycin
  • Afinitor
  • Afinitor Disperz
  • Certica
  • Certican
  • Certican(R)
  • RAD
  • See more synonyms
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Found 13 products.
  • Everolimus CRS

    CAS:
    Everolimus CRS

    Ref: 41-Y0002048

    70mg
    455.00€
  • Everolimus for system suitability A CRS

    CAS:
    Everolimus for system suitability A CRS

    Ref: 41-Y0002354

    10mg
    455.00€
  • Everolimus

    CAS:
    Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.
    Formula:C53H83NO14
    Purity:97.76% - 99.52%
    Color and Shape:Off-White To Light Yellow Powd
    Molecular weight:958.22

    Ref: TM-T1784

    5mg
    44.00€
    10mg
    55.00€
    25mg
    82.00€
    50mg
    96.00€
    100mg
    120.00€
    200mg
    177.00€
    500mg
    298.00€
    1mL*10mM (DMSO)
    55.00€
  • Everolimus

    CAS:
    Everolimus
    Purity:≥98%
    Molecular weight:958.22g/mol

    Ref: 54-BUP15400

    5mg
    59.00€
    10mg
    80.00€
    25mg
    115.00€
    50mg
    147.00€
    100mg
    187.00€
    200mg
    268.00€
  • Everolimus

    Controlled Product
    CAS:
    Impurity Everolimus EP Impurity C Stability Hygroscopic Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),
    Formula:C53H83NO14
    Purity:~90%
    Color and Shape:Neat
    Molecular weight:958.22

    Ref: TR-E945400

    5mg
    134.00€
    10mg
    178.00€
    50mg
    384.00€
  • Everolimus

    CAS:
    Formula:C53H83NO14
    Purity:≥ 98.0%
    Color and Shape:White to off-white solid
    Molecular weight:958.22

    Ref: 7W-GP1203

    1mg
    98.00€
    1ml
    404.00€
    5mg
    137.00€
    25mg
    288.00€
  • Everolimus

    CAS:
    Antibiotics nesoi
    Formula:C53H83NO14
    Color and Shape:White Yellow Powder
    Molecular weight:957.58136

    Ref: 45-1268976

    300mg
    3,094.00€
  • Everolimus

    CAS:
    mTOR kinase inhibitor; rapamycin analog; immunosuppressant
    Formula:C53H83NO14
    Purity:90%
    Color and Shape:White Off-White Powder
    Molecular weight:957.58136

    Ref: 3D-FE23209

    1g
    1,342.00€
    50mg
    233.00€
    100mg
    307.00€
    250mg
    552.00€
    500mg
    837.00€
  • Everolimus

    CAS:
    Formula:C53H83NO14
    Color and Shape:White To Off-White Solid
    Molecular weight:958.24

    Ref: 4Z-E-101

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
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    100mg
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  • Everolimus

    CAS:
    Everolimus
    Purity:98%
    Molecular weight:958.22g/mol

    Ref: 54-OR1026213

    1g
    636.00€
    5g
    2,017.00€
    100mg
    152.00€
    250mg
    242.00€
  • Everolimus, Cyclosporine and Tacrolimus Mix Standard

    Controlled Product
    CAS:
    Formula:C53H83NO14•C62H111N11O12•C44H69NO12
    Color and Shape:Mixture

    Ref: TR-E608165

    100mg
    1,151.00€
  • Rapamycin, 42-O-(2-hydroxyethyl)-

    CAS:
    Formula:C53H83NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:958.2244

    Ref: IN-DA001QMG

    1g
    600.00€
    5g
    To inquire
    10g
    3,342.00€
    5mg
    61.00€
    25mg
    79.00€
    50mg
    131.00€
    100mg
    177.00€
    250mg
    214.00€
  • Everolimus

    CAS:
    Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
    Formula:C53H83NO14
    Color and Shape:Powder or crystals or crystalline powder or granules or amorphous solid, White to off-white to pale yellow
    Molecular weight:958.24

    Ref: 02-J60139

    5mg
    To inquire
    10mg
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    25mg
    To inquire