
CAS 159351-69-6: Everolimus
Formula:C53H83NO14
InChI:InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
InChI key:InChIKey=HKVAMNSJSFKALM-GKUWKFKPSA-N
SMILES:O=C1N2[C@](C(=O)O[C@]([C@@H](C[C@H]3C[C@@H](OC)[C@H](OCCO)CC3)C)(CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(/C)\[C@@H](OC)C[C@]4(O[C@@](O)(C1=O)[C@H](C)CC4)[H])[H])(CCCC2)[H]
Synonyms:- (3S,6R,7Z,9R,10R,12R,14S,15E,17Z,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
- 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv.
- 40-O-(2-Hydroxyethyl)rapamycin
- 42-O-(2-Hydroxy)ethyl rapamycin
- 42-O-(2-Hydroxyethyl)-rapamycin
- Afinitor
- Afinitor Disperz
- Certica
- Certican
- Certican(R)
- RAD
- See more synonyms
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Found 13 products.
Everolimus
CAS:Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.Formula:C53H83NO14Purity:97.76% - 99.52%Color and Shape:Off-White To Light Yellow PowdMolecular weight:958.22Ref: TM-T1784
5mg44.00€10mg55.00€25mg82.00€50mg96.00€100mg120.00€200mg177.00€500mg298.00€1mL*10mM (DMSO)55.00€Everolimus
CAS:Controlled ProductImpurity Everolimus EP Impurity C Stability Hygroscopic Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),Formula:C53H83NO14Purity:~90%Color and Shape:NeatMolecular weight:958.22Everolimus
CAS:Formula:C53H83NO14Purity:≥ 98.0%Color and Shape:White to off-white solidMolecular weight:958.22Everolimus
CAS:Antibiotics nesoiFormula:C53H83NO14Color and Shape:White Yellow PowderMolecular weight:957.58136Everolimus
CAS:mTOR kinase inhibitor; rapamycin analog; immunosuppressantFormula:C53H83NO14Purity:90%Color and Shape:White Off-White PowderMolecular weight:957.58136Everolimus, Cyclosporine and Tacrolimus Mix Standard
CAS:Controlled ProductFormula:C53H83NO14•C62H111N11O12•C44H69NO12Color and Shape:MixtureRapamycin, 42-O-(2-hydroxyethyl)-
CAS:Formula:C53H83NO14Purity:98%Color and Shape:SolidMolecular weight:958.2244Ref: IN-DA001QMG
1g600.00€5gTo inquire10g3,342.00€5mg61.00€25mg79.00€50mg131.00€100mg177.00€250mg214.00€Everolimus
CAS:Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C53H83NO14Color and Shape:Powder or crystals or crystalline powder or granules or amorphous solid, White to off-white to pale yellowMolecular weight:958.24