CAS: 15978-07-1

α-D-Mannose 1-phosphate is a complex carbohydrate that is modified with methylation, glycosylation and fluorination. This product has been custom synthesized to order. It is an oligosaccharide that can be modified with glycosylation and carbonylation. Methylation of α-D-mannose 1-phosphate leads to the formation of a fluorinated sugar called α-D-mannose 1,6-diphosphate. The modification process can be done in several ways, including Click chemistry. This product is of high purity and has been synthesized from natural materials.

Applications α-D-Mannose 1-Phosphate is used in the synthesis of non-natural mannoglucans by α-glucan phosphorylase-catalyzed enzymatic copolymerization;Also, it is derived from D-Mannose (M168000), which is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in infant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule. References Baba, R., et al.: Carbohydr. Polym., 151, 1034-1039 (2016); van Leeuwen, S. et al.: J. Agri. Food Chem., 60, 12553 (2012); Geoghegan, K. et al.: Prot. Express. Purif., 87, 27 (2013);