Phenol, 4-amino-2,6-dimethyl- (CAS 15980-22-0) is an organic compound characterized by the presence of a phenolic hydroxyl group and an amino group attached to a substituted aromatic ring. This compound features two methyl groups at the 2 and 6 positions of the benzene ring, which contribute to its hydrophobic character and influence its reactivity. The amino group, located at the para position relative to the hydroxyl group, enhances the compound's basicity and can participate in hydrogen bonding, affecting its solubility in polar solvents. Phenol derivatives, including this compound, are often used in the synthesis of dyes, pharmaceuticals, and agrochemicals due to their functional properties. The presence of both the hydroxyl and amino groups allows for various chemical reactions, including electrophilic substitution and nucleophilic addition. Additionally, the compound may exhibit biological activity, making it of interest in medicinal chemistry. Safety precautions should be taken when handling this substance, as phenolic compounds can be toxic and irritant to skin and mucous membranes.

Phenol, 4-amino-2,6-dimethyl-

4-Amino-2,6-dimethylphenol is a chemical compound that belongs to the class of arylating agents. It reacts with glutathione in the liver, forming an imine. This reaction results in glutathione depletion and cellular toxicity. The cytotoxic effect of 4-Amino-2,6-dimethylphenol has been shown in rat liver microsomes and rat liver cells. In addition, it induces oxidative stress by reacting with intracellular glutathione and causing sulphydryl groups to be oxidized to disulphides. 4-Amino-2,6-dimethylphenol also inhibits the activity of microsomal drug metabolizing enzymes such as cytochrome P450 enzymes.

CAS 15980-22-0: Phenol, 4-amino-2,6-dimethyl-

4-Amino-2,6-dimethylphenol

Ref: 3D-FA120261

Phenol, 4-amino-2,6-dimethyl-

Ref: IN-DA001RF3

4-Amino-2,6-dimethylphenol

Ref: 10-F617841