CAS: 1598426-03-9

CG347B

CG347B is a selective inhibitor of HDAC6.

CG347B is a synthetic glucocorticoid-receptor-binding molecule, which is derived from laboratory-based chemical synthesis focused on modulating glucocorticoid receptor pathways. This compound works through selective glucocorticoid receptor engagement, inducing changes in gene expression that replicate aspects of natural hormone binding but with distinct specificity and kinetics. Its applications are extensively found in the study of inflammatory pathways, where it is utilized to help delineate the complex roles of glucocorticoids in cellular responses. Additionally, it serves as a critical tool in pharmacological research to investigate receptor-ligand interactions, enabling the dissection of receptor-mediated signaling mechanisms. By providing researchers with a robust framework to explore receptor dynamics, CG347B aids in uncovering potential therapeutic targets for treating inflammatory and immune-mediated conditions, as well as advancing understanding of hormone-responsive gene regulatory networks.