![N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitr…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F350510-n-6-25-dihydro-25-dioxo-1h-pyrrol-1-yl-1-oxohexyl-l-valyl-n5-aminocarbonyl-n-4-4-nitrophenoxy-carbonyl-oxy-methyl-phenyl-l-ornithinamide.webp&w=3840&q=75)
CAS 159857-81-5: N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-L-ornithinamide
Formula:C35H43N7O11
InChI:InChI=1S/C35H43N7O11/c1-22(2)31(40-28(43)8-4-3-5-20-41-29(44)17-18-30(41)45)33(47)39-27(7-6-19-37-34(36)48)32(46)38-24-11-9-23(10-12-24)21-52-35(49)53-26-15-13-25(14-16-26)42(50)51/h9-18,22,27,31H,3-8,19-21H2,1-2H3,(H,38,46)(H,39,47)(H,40,43)(H3,36,37,48)/t27-,31-/m0/s1
InChI key:InChIKey=HYSPJPGXSALJRR-DHIFEGFHSA-N
SMILES:[C@H](C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)=O)(NC([C@@H](NC(CCCCCN3C(=O)C=CC3=O)=O)C(C)C)=O)CCCNC(N)=O
Synonyms:- Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
- 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate
- MC-Val-Cit-PAB-PNP
- N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-L-ornithinamide
- L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
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Found 8 products.
L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-
CAS:Formula:C35H43N7O11Purity:98%Color and Shape:SolidMolecular weight:737.7562Mc-Val-Cit-PABC-PNP
CAS:Controlled ProductFormula:C35H43N7O11Color and Shape:NeatMolecular weight:737.756MC-Val-Cit-PABC-PNP
CAS:MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.Formula:C35H43N7O11Purity:97.2% - 99.13%Color and Shape:SolidMolecular weight:737.76Mc-Val-Cit-PABC-PNP
CAS:Formula:C35H43N7O11Purity:>97.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalineMolecular weight:737.77Mc-Val-Cit-PABC-PNP
CAS:Mc-Val-Cit-PABC-PNP is a modified form of epidermal growth factor (EGF) that is conjugated to the cytotoxic agent, Cetuximab. EGF can act as a growth factor for tumor cells, which makes it an attractive target for cancer therapy. The conjugation of the cytotoxic agent to EGF can lead to potent cytotoxicity against tumor cells. In addition, cetuximab may also bind to the receptor on the surface of cancer cells and inhibit their growth. This product has shown potential in treatment of cancers such as colorectal cancer and head and neck cancers.Formula:C35H43N7O11Purity:Min. 95%Color and Shape:White PowderMolecular weight:737.76 g/mol