Taxane refers to a class of chemical compounds derived from the yew tree, particularly Taxus species. The specific compound associated with the CAS number 1605-68-1 is paclitaxel, a well-known taxane used primarily in cancer therapy. Paclitaxel is characterized by its complex polycyclic structure, which includes a taxane core with a unique arrangement of functional groups. It exhibits a high degree of lipophilicity, which influences its solubility and bioavailability. The mechanism of action of paclitaxel involves the stabilization of microtubules, preventing their depolymerization, thereby inhibiting cell division and leading to apoptosis in rapidly dividing cancer cells. This property makes it effective against various types of cancers, including ovarian, breast, and lung cancers. Additionally, paclitaxel has a relatively low oral bioavailability, often necessitating intravenous administration. Its side effects can include myelosuppression, neuropathy, and hypersensitivity reactions, which are important considerations in clinical settings. Overall, taxanes like paclitaxel play a significant role in modern oncology due to their potent antitumor activity.

taxane

1605-68-1: (4R,4aR,6S,9R,10S,12aR)-Tetradecahydro-4,9,12a,13,13-pentamethyl-6,10-methanobenzocyclodecene, 6,10-Methanobenzocyclodecene, tetradecahydro-4,9,12a,13,13-pentamethyl-, (4R,4aR,6S,9R,10S,12aR)-, 6,10-Methanobenzocyclodecene, tetradecahydro-4,9,12a,13,13-pentamethyl-, (4R-(4alpha,4abeta,6alpha,9alpha,10alpha,12aalpha))-, 6,10-Methanobenzocyclodecene, tetradecahydro-4,9,12a,13,13-pentamethyl-, [4R-(4α,4aβ,6α,9α,10α,12aα)]-, Taxan, Taxane

Taxane

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CAS 1605-68-1: taxane

Taxane

Ref: 4Z-P-2851

Taxane

Ref: 3D-BAA60568

Taxane

Ref: TR-T009800