3'-Deoxy-5'-O-trityl-D-uridine is a modified nucleoside that plays a significant role in biochemical research and synthetic chemistry, particularly in the field of oligonucleotide synthesis. This compound features a uridine base, which is a nucleoside composed of a pyrimidine ring (uracil) linked to a ribose sugar. The "3'-deoxy" modification indicates the absence of a hydroxyl group at the 3' position of the sugar, which enhances its stability and resistance to enzymatic degradation. The "5'-O-trityl" designation refers to the presence of a trityl protecting group at the 5' position, which is commonly used to protect the hydroxyl group during chemical reactions. This modification allows for selective reactions at other positions of the nucleoside. Overall, 3'-Deoxy-5'-O-trityl-D-uridine is utilized in the synthesis of oligonucleotides and other nucleic acid derivatives, facilitating the study of nucleic acid interactions and functions in various biological contexts.

3'-Deoxy-5'-O-trityl-D-uridine

161110-05-0: Uridine, 3′-deoxy-5′-O-(triphenylmethyl)-

3'-Deoxy-5'-O-trityluridine is a nucleoside that is structurally related to uridine. It belongs to the class of nucleosides and has a hydroxyl group at the 3' position. The 5' position is modified by an anion (most often trityl) sterically, which prevents hydrolysis by esterases or phosphatases. The efficiency of this modification can be increased by using diethyl phosphate as the protecting agent. This modification also provides protection against nucleophiles, such as hydroxyl groups in nucleosides or phosphite triester derivatives. 3'-Deoxy-5'-O-trityluridine is used in the synthesis of other nucleosides and as a substrate for diffraction experiments.

CAS 161110-05-0: 3'-Deoxy-5'-O-trityl-D-uridine

3'-Deoxy-5'-O-trityluridine

Ref: 3D-ND05370

3''-Deoxy-5''-O-trityluridine

Ref: 7W-GN7031

Uridine, 3'-deoxy-5'-O-(triphenylmethyl)- (9CI)

Ref: IN-DA001S67