Pozanicline, identified by its CAS number 161417-03-4, is a chemical compound that functions primarily as a selective alpha-7 nicotinic acetylcholine receptor agonist. This compound has garnered interest in pharmacological research, particularly for its potential therapeutic applications in cognitive disorders, such as Alzheimer's disease and schizophrenia. Pozanicline exhibits a unique mechanism of action that enhances cholinergic neurotransmission, which is crucial for cognitive processes like learning and memory. Its selectivity for the alpha-7 receptor subtype is significant, as this receptor is implicated in various neurobiological functions and is a target for drug development aimed at improving cognitive function. The compound's pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its efficacy and safety profile in clinical settings. Ongoing studies continue to explore its potential benefits and side effects, contributing to the understanding of its role in neuropharmacology.

Pozanicline

161417-03-4: (S)-2-Methyl-3-(2-pyrrolidinylmethoxy)pyridine, 2-Methyl-3-(2S-pyrrolidinylmethoxy)pyridine, 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]pyridine, 2-Methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine, A 87089.0, Abt 089, Pozanicline, Pyridine, 2-methyl-3-((2S)-2-pyrrolidinylmethoxy)-, Pyridine, 2-methyl-3-(2-pyrrolidinylmethoxy)-, (S)-, Unii-Cl2002R563

Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.

Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-

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CAS 161417-03-4: Pozanicline

Pozanicline

Ref: TM-T16563

Pyridine, 2-methyl-3-[(2S)-2-pyrrolidinylmethoxy]-

Ref: IN-DA001SGG

ABT-089

Ref: 3D-LGA41703