CAS: 1620820-12-3

TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.

TL4-12 is a gene editing tool, which is a synthetic construct engineered through advanced biotechnological techniques. It operates via CRISPR-Cas9 technology, enabling the precise targeting and modification of specific genomic sequences in living cells. The Cas9 enzyme acts as molecular scissors, guided by a custom RNA sequence within TL4-12 to a unique DNA target location. This tool is utilized in a range of applications, including genomic research, functional gene studies, and therapeutic genome editing. TL4-12 allows scientists to investigate gene function, understand genetic disorders, and potentially correct pathogenic mutations. With its high specificity and efficiency, it contributes significantly to advancements in genetic therapy and molecular biology research, providing a powerful resource in the ongoing exploration of gene function and regulation.

TL4-12