CAS 16220-07-8: allopurinol riboside
Formula:C10H12N4O5
InChI:InChI=1S/C10H12N4O5/c15-2-5-6(16)7(17)10(19-5)14-8-4(1-13-14)9(18)12-3-11-8/h1,3,5-7,10,15-17H,2H2,(H,11,12,18)/t5-,6-,7-,10-/m1/s1
InChI key:InChIKey=KFQUAMTWOJHPEJ-DAGMQNCNSA-N
SMILES:O[C@H]1[C@H](N2C3=C(C=N2)C(=O)N=CN3)O[C@H](CO)[C@H]1O
Synonyms:- 1,5-Dihydro-1-beta-D-ribofuranosyl-4H-pyrazolo(3,4-d)pyrimidin-4-one
- 1,5-Dihydro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one
- 1-(beta-D-ribofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
- 1-(beta-L-ribofuranosyl)-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
- 1-[(2S,3S,4R,5R)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl]-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (non-preferred name)
- 1-pentofuranosyl-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
- 4-Hydroxy(3,4-d)pyrazolopyrimidine riboside
- 4-Hydroxy-1beta-D-ribofuranosylpyrazolo(3,4-d)pyrimidine
- 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-beta-D-ribofuranosyl-
- 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- Allopurinol ribonucleoside
- See more synonyms
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Found 8 products.
4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-β-D-ribofuranosyl-
CAS:Formula:C10H12N4O5Purity:98%Molecular weight:268.2261Allopurinol riboside
CAS:Allopurinol riboside, an allopurinol metabolite, inhibits purine nucleoside phosphorylase in parasites with a Ki of 277 μM.Formula:C10H12N4O5Purity:100% - 99.21%Color and Shape:SolidMolecular weight:268.23Allopurinol riboside
CAS:Controlled ProductFormula:C10H12N4O5Color and Shape:NeatMolecular weight:268.226Allopurinol riboside
CAS:Allopurinol riboside is a hydroxyl analog of allopurinol. Allopurinol riboside has minimal toxicity in tissue culture and exhibits no cytotoxicity in human serum. It is a potent inhibitor of microbial infection, including infections caused by Hepatitis C virus (HCV), Leishmania amazonensis, and Mycobacterium tuberculosis. Allopurinol riboside binds to adenine nucleotide and inhibits the synthesis of purines, which are necessary for DNA replication. This binding also inhibits the production of ATP, leading to cell death. In addition, allopurinol riboside inhibits the growth of human macrophages in vitro by inhibiting protein synthesis. Allopurinol riboside may be useful for treating HCV-induced liver disease or leishmaniasis.Formula:C10H12N4O5Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:268.23 g/mol
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