CAS: 1622848-92-3
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(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
CAS:Purity:95.0%Molecular weight:377.40399169921875(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide
CAS:Formula:C20H19N5O3Purity:99%Color and Shape:SolidMolecular weight:377.3965599999999GSK 2982772
CAS:An ultraselective, first-in-class inhibitor of the Receptor Interacting Protein 1 (RIP1) kinase with nanomolar potency. The compound occupies allosteric pockets characteristic of type II and type III classes of kinase inhibitors. It blocks the TNF-induced necrotic cell death and reduces the production of cytokines IL-1β and IL-6 from ulcerative colitis explant tissue. Potential candidate for treatment of inflammatory diseases such as psoriasis, ulcerative colitis and rheumatoid arthritis.Formula:C20H19N5O3Purity:Min. 95%Molecular weight:377.4 g/mol(S)-3-Benzyl-N-(5-Methyl-4-Oxo-2,3,4,5-Tetrahydrobenzo[b][1,4]Oxazepin-3-Yl)-1H-1,2,4-Triazole-5-Carboxamide
CAS:(S)-3-Benzyl-N-(5-Methyl-4-Oxo-2,3,4,5-Tetrahydrobenzo[b][1,4]Oxazepin-3-Yl)-1H-1,2,4-Triazole-5-CarboxamideMolecular weight:377.4g/molGSK2982772
CAS:GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.Formula:C20H19N5O3Purity:99.27% - 99.31%Color and Shape:SolidMolecular weight:377.4
![(S)-5-BENZYL-N-(5-METHYL-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-3-C…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF539520.jpg&w=3840&q=75)
![(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-c…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00AQYH.jpg&w=3840&q=75)
![(S)-3-Benzyl-N-(5-Methyl-4-Oxo-2,3,4,5-Tetrahydrobenzo[b][1,4]Oxazepin-3-Yl)-1H-1,2,4-Triazole-5-C…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1023972.jpg&w=3840&q=75)
