
CAS: 1629063-81-5
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Found 3 products.
GNE-131
CAS:GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).Formula:C23H30N4O3SPurity:98.54% - 99.59%Color and Shape:SolidMolecular weight:442.57Ref: TM-TQ0014
1mg120.00€5mg264.00€10mg376.00€25mg630.00€50mg880.00€100mg1,169.00€1mL*10mM (DMSO)283.00€GNE 131
CAS:A triazole sulphonamide that selectively inhibits sodium channel NaV1.7, by binding to the VSD4 site. GNE 131 demonstrated high potency and metabolic stability in vitro. NaV1.7 is a potential target for the treatment of pain, due to its role in nociception. It has high efficacy in transgenic mouse model of induced pain.Formula:C23H30N4O3SPurity:Min. 95%Molecular weight:442.58 g/mol