CAS 1630-82-6: 4-Bromo-3-hydroxyestra-1,3,5(10)-trien-17-one
Formula:C18H21BrO2
InChI:InChI=1S/C18H21BrO2/c1-18-9-8-11-10-4-6-15(20)17(19)13(10)3-2-12(11)14(18)5-7-16(18)21/h4,6,11-12,14,20H,2-3,5,7-9H2,1H3/t11-,12-,14+,18+/m1/s1
InChI key:InChIKey=NQFVJAYQCZUYON-QDTBLXIISA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=C(Br)C(O)=CC4)(CC1)[H])[H])(CCC2=O)[H]
Synonyms:- Estra-1,3,5(10)-trien-17-one, 4-bromo-3-hydroxy-
- 4-Bromo-3-hydroxyestra-1,3,5(10)-trien-17-one
- 4-Bromoestrone
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Found 2 products.
4-Bromoestrone
CAS:Controlled Product4-Bromoestrone is a synthetic estrogen that has been shown to be useful in the treatment of breast cancer. It has been used as an antineoplastic drug, which is a substance that slows the growth of abnormal cells. 4-Bromoestrone can be acetylated by a nitro group and then converted into 4-bromotamoxifen (4-BT), which is a potent anti-tumor agent. The structure of 4-bromoestrone resembles that of estrogens, but it lacks the C2 methyl group found on estradiol and other estrogens, which makes it more difficult for enzymes to convert it into other estrogens. 4-Bromoestrone binds with high affinity to estrogen receptors and can activate them without requiring any cofactors or cofactors. This means that the drug has no effect on tissues that do not contain these receptors.Formula:C18H21BrO2Purity:Min. 95%Molecular weight:349.3 g/mol4-Bromoestrone (>90%)
CAS:Controlled ProductFormula:C18H21BrO2Purity:>90%Color and Shape:NeatMolecular weight:349.26
