CAS 16320-04-0: Gestrinone
Formula:C21H24O2
InChI:InChI=1S/C21H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,9,11,13,18-19,23H,3,5-8,10,12H2,1H3/t18-,19+,20+,21+/m1/s1
InChI key:InChIKey=BJJXHLWLUDYTGC-ANULTFPQSA-N
SMILES:C(C)[C@@]12[C@]([C@]3(C(C=C1)=C4C(CC3)=CC(=O)CC4)[H])(CC[C@]2(C#C)O)[H]
Synonyms:- (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-20-yn-3-one
- (8S,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- 13-Ethyl-17-alpha-ethinyl-17-hydroxygon-4,9,11-trien-3-one
- 13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregna-4,9,11-trien-20-yn-3-one
- 13-Ethyl-17α-ethynyl-17β-hydroxygona-4,9,11-trien-3-one
- 13-beta-Ethyl-17-alpha-ethinyl-17-hydroxy-gona-4,9,11-triene-3-one
- 18,19-Dinor-17-alpha-pregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-
- 18,19-Dinor-17α-pregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-
- 18,19-Dinorpregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha)- (9CI)
- 18,19-Dinorpregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-
- A 46745
- See more synonyms
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Found 9 products.
Gestrinone
CAS:Controlled ProductGestrinone is a synthetic steroidal hormone that binds to the progesterone receptor. It has been used in the treatment of endometriosis, although its efficacy is questionable. Gestrinone is a potent inhibitor of cyclooxygenase and lipoxygenase, which leads to an anti-inflammatory effect. Gestrinone also suppresses gonadotropin secretion from the pituitary gland by reducing gonadotropin-releasing hormone (GnRH) release. The drug has been found to have contraceptive activity in vivo and in vitro, but it does not appear to inhibit ovulation or fertilization. Gestrinone inhibits estrogen synthesis by blocking the conversion of estradiol benzoate into estradiol during pregnancy. This drug also inhibits aromatase activity and has been shown to be effective against endometriosis in humans. However, gestrinone is associated with side effects such as nausea, breast tenderness, weight gain, headache, depression and fatigueFormula:C21H24O2Purity:Min. 95%Molecular weight:308.41 g/mol6alpha-Hydroxy Gestrinone Glucuronide
CAS:Controlled ProductFormula:C27H32O9Color and Shape:Light YellowMolecular weight:500.54Gestrinone-d3 (major)
CAS:Controlled ProductFormula:C21D3H21O2Color and Shape:NeatMolecular weight:311.433Gestrinone
CAS:Formula:C21H24O2Purity:>98.0%(T)Color and Shape:Light yellow to Yellow powder to crystalMolecular weight:308.4218,19-Dinorpregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-
CAS:Formula:C21H24O2Purity:99%Color and Shape:SolidMolecular weight:308.4141Ref: IN-DA001TUP
Discontinued productGestrinone (1mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C21H24O2Color and Shape:Single SolutionMolecular weight:308.40Gestrinone
CAS:Gestrinone (R 2323) 是一种合成类固醇激素,能够抑制平滑肌瘤(IC50:43.67 μM),有用于子宫内膜异位症的研究潜力。Formula:C21H24O2Purity:99.21%Color and Shape:Light Yellow SolidMolecular weight:308.41Gestrinone
CAS:Controlled ProductApplications Gestrinone is a Steroidal antiestrogen, antiprogestogen, analog of Norgestrienone. Antigonadotropin.Controlled substance. References Azadian-Boulanger, G., et al.: Am. J. Obstet. Gynecol., 125, 1049 (1976), Thomas, E.J., et al.: Br. Med. J., 294, 272 (1987), Coutinho, E.M., et al.: Fertil. Steril., 49, 418 (1988),Formula:C21H24O2Color and Shape:Off-White To Dark YellowMolecular weight:308.40
