2-Hydroxy-5-nitroindane is an organic compound characterized by its indane structure, which consists of a fused benzene and cyclopentane ring. The presence of a hydroxyl group (-OH) at the 2-position and a nitro group (-NO2) at the 5-position contributes to its chemical reactivity and properties. This compound typically exhibits moderate solubility in polar solvents due to the hydroxyl group, while the nitro group can influence its electronic properties, making it a potential candidate for various chemical reactions, including nitration and reduction processes. The presence of these functional groups may also impart biological activity, making it of interest in medicinal chemistry. Additionally, 2-hydroxy-5-nitroindane may undergo various transformations under different conditions, leading to the formation of derivatives that could have distinct physical and chemical properties. As with many nitro compounds, it is essential to handle this substance with care due to potential toxicity and environmental concerns.

2-HYDROXY-5-NITROINDANE

16513-67-0: 5-nitro-2,3-dihydro-1H-inden-2-ol

2-Hydroxy-5-nitroindane is a synthetic retinoid that binds to the retinoic acid receptor, which induces antiproliferative activity. It has been found to be a potent inhibitor of cell proliferation and an inducer of differentiation in vitro. 2-Hydroxy-5-nitroindane alters the expression of genes involved in the process of apoptosis and inhibits DNA synthesis by binding to DNA. This compound also has an affinity for the skeleton, which may be due to its ability to bind with benzoic acid. 2-Hydroxy-5-nitroindane has been shown to inhibit tumor growth in vivo, although it does not inhibit tumor initiation or tumor promotion.

CAS 16513-67-0: 2-HYDROXY-5-NITROINDANE

2-Hydroxy-5-nitroindane

Ref: 3D-RAA51367

1H-Inden-2-ol, 2,3-dihydro-5-nitro-

Ref: IN-DA001VB1

5-Nitro-2,3-dihydro-1H-inden-2-ol

Ref: 10-F437862