3-Methoxy Loratadine, identified by its CAS number 165739-73-1, is a derivative of loratadine, which is an antihistamine commonly used to alleviate allergy symptoms. This compound features a methoxy group (-OCH3) at the 3-position of the loratadine structure, which may influence its pharmacological properties. Typically, substances like 3-Methoxy Loratadine exhibit low solubility in water but may have better solubility in organic solvents, reflecting the presence of hydrophobic aromatic rings in their structure. The compound is expected to possess anti-allergic properties, similar to its parent compound, by acting as a selective antagonist of peripheral H1 receptors. Additionally, it may exhibit a favorable pharmacokinetic profile, including good oral bioavailability and a relatively long half-life, which are characteristic of many antihistamines. However, specific data on its efficacy, safety, and side effects would require further investigation through clinical studies. Overall, 3-Methoxy Loratadine represents a potential candidate for allergy treatment, warranting further research into its therapeutic applications.

3-Methoxy Loratadine

165739-73-1: 4-(8-Chloro-5,6-dihydro-3-methoxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester, ethyl 4-(8-chloro-3-methoxy-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate

Please enquire for more information about 3-Methoxy loratadine including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Methoxy loratadine

Applications Useful as inhibitor of both farnesyl protein transferase and geranylgeranyl protein transferase in the treatment of cell-proliferative diseases.
References Villani, et al.: J. Med. Chem., 15, 750 (1972),


CAS 165739-73-1: 3-Methoxy Loratadine

3-Methoxy loratadine

Ref: 3D-FM25182

3-Methoxy Loratadine

Ref: TR-M262640