CAS 16606-02-3: PCB 31

2,4',5-Trichlorobiphenyl is a polychlorinated biphenyl that has been shown to have a high toxicity. It has been detected in human serum and wastewater samples at high levels. 2,4',5-Trichlorobiphenyl inhibits mitochondrial membrane potential, which causes a decrease in ATP production and leads to cell death. This chemical also induces the activity of cytochrome P450 enzymes, leading to increased lipid peroxidation and acid formation. This chemical is metabolized by the liver to produce many other metabolites including 2,3',4',5'-tetrachlorobiphenyl and 2,3',4',6'-tetrachlorobiphenyl. These metabolites are then excreted through urine or bile into the environment where they can be found in water or soil.