CAS 166322-14-1: 2-Propenoic acid,3-(4-hydroxy-3-methoxyphenyl)-,[(2S,3R,4R)-tetrahydro-2-(4-hydroxy-3,5-dimethoxyphenyl)-4-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-3-furanyl]methylester, (2E)-

(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol potentially inhibits histamine and is cytotoxic to some cancer cells; ED50 9.86-12.68 µg/ml.

9-o-Feruloyl-5,5'-dimethoxylariciresinol is a lignan derivative, which is a type of polyphenolic compound. This product is sourced from various plant species, particularly in seeds and roots, where it acts as a secondary metabolite integral to plant defense mechanisms. It is characterized by its complex molecular structure, involving methoxy groups and feruloyl moieties, which contribute to its biological activity. The mode of action of 9-o-Feruloyl-5,5'-dimethoxylariciresinol involves its function as an antioxidant. It mitigates oxidative stress by neutralizing free radicals, thereby preventing cellular damage. This property is of significant interest in understanding how such compounds can contribute to cellular protection and overall health. In terms of uses and applications, it is primarily used in scientific research focused on exploring natural antioxidant sources. Its potential roles are being investigated in areas such as disease prevention, particularly in conditions linked to oxidative stress, like cardiovascular diseases and certain cancers. As an area of ongoing study, it provides insight into the benefits of plant-derived compounds and their therapeutic potential.