CAS: 166527-00-0

Impurity Agomelatine Impurity 9; Agomelatine 7-Desmethyl-3-Hydroxy Impurity Applications 7-Desmethyl-3-hydroxyagomelatine is a 1-(aminoethyl)naphthalene derivative with potential binding affinity for melatonin receptors. Agomelatine Impurity 9 Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

7-Desmethyl-3-hydroxyagomelatine, less active than parent drug Agomelatine, is a melatonergic agonist and 5-HT2C antagonist.

3-Hydroxy-7-desmethyl agomelatine is a synthetic analogue of melatonin that has been shown to have potent antidepressant effects. It is a ligand for the MT1 and MT2 receptors, which are involved in the regulation of circadian rhythm. 3-Hydroxy-7-desmethyl agomelatine also binds to ion channels, such as the voltage gated sodium channels and potassium channels, with high affinity. It is used as a research tool to study protein interactions and receptor function.