
CAS 16710-13-7: 6-methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
Formula:C10H14N2O6
InChI:InChI=1/C10H14N2O6/c1-4-2-6(14)11-10(17)12(4)9-8(16)7(15)5(3-13)18-9/h2,5,7-9,13,15-16H,3H2,1H3,(H,11,14,17)
SMILES:Cc1cc(nc(=O)n1C1C(C(C(CO)O1)O)O)O
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6-Methyluridine
CAS:Nucleosides and Reagents - 6-Modified pyrimidine nucleosideFormula:C10H14N2O6Color and Shape:SolidMolecular weight:258.23Ref: TM-TNU0134
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CAS:Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.Formula:C10H14N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:258.23 g/mol6-Methyluridine
CAS:Controlled ProductApplications 6-Methyluridine exhibited weak antimalarial activity against P. falciparum 3D7 isolate. It is a weak substrate of Escherichia coli pyrimidine nucleoside phosphorylase. References Bello, A., et al.: J. Med. Chem., 51, 439 (2008); Felczak, K., et al.: J. Med. Chem., 39, 1720 (1996)Formula:C10H14N2O6Color and Shape:NeatMolecular weight:258.23