CAS 168701-80-2: 8-NITROGUANINE
Formula:C5H4N6O3
InChI:InChI=1/C5H4N6O3/c6-4-8-2-1(3(12)10-4)7-5(9-2)11(13)14/h(H4,6,7,8,9,10,12)
SMILES:c12c([nH]c(=N)nc1O)[nH]c(n2)N(=O)=O
Synonyms:- 8-No2-Gua
- 2-amino-8-nitro-3,7-dihydro-6H-purin-6-one
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Found 4 products.
8-Nitroguanine
CAS:Controlled ProductApplications 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer. References Surh, Y., et al.: Mutat. Res., 480, 243 (2001), Balkwill, F., et al.: Lancet, 357, 539 (2001), Kawanishi, S., et al.: Biol. Chem., 387, 365 (2006), Hoki, Y., et al.: Cancer Sci., 98, 163 (2007),Formula:C5H4N6O3Color and Shape:NeatMolecular weight:196.128-Nitroguanine
CAS:8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignantFormula:C5H4N6O3Color and Shape:SolidMolecular weight:196.126H-Purin-6-one, 2-amino-1,9-dihydro-8-nitro-
CAS:Formula:C5H4N6O3Color and Shape:SolidMolecular weight:196.12378-Nitroguanine
CAS:8-Nitroguanine is a reactive cell factor that can be found in the skin and other tissues. It is an endogenous product of nitric oxide, which can be formed by the reaction of nitric oxide with superoxide in the presence of peroxynitrite. 8-Nitroguanine has been shown to inhibit matrix metalloproteinase-9 activity and to have a protective effect on cells from UV radiation. 8-Nitroguanine also has been shown to be a potential biomarker for bowel disease and damage. The levels of 8-nitroguanine increase in chronic viral hepatitis and cancer tissues. This compound can also be used as an analytical method for detection of inflammation, oxidative stress, or DNA damage.Formula:C5H4N6O3Purity:Min. 95%Color and Shape:PowderMolecular weight:196.13 g/mol
