CAS 16879-02-0: 6-Chloro-2(1H)-pyridinone

6-chloro-2-hydroxypyridine was used to study the synthesis, electrochemistry, spectroscopic properties and X-ray crystal structure of Os2Cl(chp)4 (chp = 6-chloro-2- hydroxypyridinate) complex. It undergoes melt reaction with Os2(O2CCH3)4CI2 at 145°C to yield Os2CI4(chp) and Os2Cl(chp)4. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

6-Chloro-2-hydroxypyridine

2-Chloro-6-hydroxypyridine is an organic compound with a molecular formula of C5H3ClN3O. It is the simplest aromatic heterocycle that contains a hydroxyl group. 2-Chloro-6-hydroxypyridine is a colorless crystalline solid and it has been extensively used as a model system for the study of nucleophilic substitution reactions. This compound can be prepared by reacting sodium salts with hydrochloric acid and then heating the solution to evaporate water. The X-ray crystal structure of this molecule reveals that it has three tautomers, which are interconvertible by oxidation or reduction. Chemical biology studies have shown that 2-Chloro-6-hydroxypyridine can be activated by copper to form reactive oxygen species such as peroxides, superoxide, and hydrogen peroxide in biological systems.