CAS 170632-47-0: Lificiguat
Formula:C19H16N2O2
InChI:InChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
InChI key:InChIKey=OQQVFCKUDYMWGV-UHFFFAOYSA-N
SMILES:C(N1N=C(C=2C1=CC=CC2)C=3OC(CO)=CC3)C4=CC=CC=C4
Synonyms:- 1-Benzyl-3-(5-hydroxymethyl-furan-2-yl)indazole
- 1-Benzyl-3-(5-hydroxymethylfur-2-yl)indazole
- 2-Furanmethanol, 5-[1-(phenylmethyl)-1H-indazol-3-yl]-
- 5-[1-(Phenylmethyl)-1H-Indazol-3-Yl]-2-Furanmethanol
- Lificiguat
- YC 1 (pharmaceutical)
- Yc-1 (3-(5'-Hydroxymethyl-2'-Furyl)-1-Be Nzyl Indazole) \ Guanylyl Cyclase Acti
- [5-(1-Benzyl-1H-indazol-3-yl)-furan-2-yl]-methanol
- [5-(1-Benzylindazol-3-yl)furan-2-yl]methanol
- YC 1
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Found 6 products.
Lificiguat
CAS:Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alphaFormula:C19H16N2O2Purity:98.85% - 99.92%Color and Shape:SolidMolecular weight:304.34Ref: TM-T4381
5mg50.00€10mg66.00€25mg125.00€50mg240.00€100mg410.00€200mg607.00€500mg938.00€1mL*10mM (DMSO)52.00€YC-1
CAS:YC-1 is an activator of soluble guanylate cyclase (sGC), derived from synthetic chemical sources, with a specific mode of action that inhibits the degradation of cyclic guanosine monophosphate (cGMP). By modulating the levels of cGMP, YC-1 affects various biological pathways associated with vasodilation, anti-platelet aggregation, and anti-inflammatory effects. Scientifically, YC-1 has garnered attention for its potent effect on sGC, disrupting the conventional phosphorylation cascades that regulate vascular tone and platelet activity. The molecule effectively prolongs the signal transduction of nitric oxide (NO) by stabilizing its interaction with sGC, thus enhancing the downstream cGMP effects. Its uses and applications are diverse, including research into cardiovascular diseases, where it serves as a potential therapeutic agent to mitigate conditions like hypertension and thromboembolism. Additionally, its anti-tumor properties are being explored, targeting pathways that affect tumor growth and metastasis. As a research tool, YC-1 provides a valuable method for probing the cellular and molecular mechanisms underlying sGC-related pathways, offering insights that could lead to the development of new therapeutic strategies for a range of diseases.Formula:C19H16N2O2Purity:Min. 95%Molecular weight:304.34 g/mol(5-(1-Benzyl-1H-Indazol-3-Yl)Furan-2-Yl)Methanol
CAS:(5-(1-Benzyl-1H-Indazol-3-Yl)Furan-2-Yl)MethanolPurity:98%Molecular weight:304.34g/mol
