CAS 1708-29-8: 2,5-Dihydrofuran

2,5-Dihydrofuran is a reactive organic molecule that contains two hydrogens and two carbon atoms. The optimal energy for the reaction of 2,5-dihydrofurans with hydrogen fluoride is low, which makes it a good reactant in acid conditions. 2,5-Dihydrofuran has been shown to be an intermediate in the formation of ethyne by transfer reactions. The histological analysis of cells treated with 1% 2,5-dihydrofuran showed a decrease in the number of cells with an intact nucleus. The isotopomer distribution data revealed that the concentration of 2,5-dihydrofurans increased after treatment with hydrogen fluoride. These results suggest that 2,5-dihydrofurans are formed by the reaction between hydrogen fluoride and ethyne.

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Applications 2,5-Dihydrofuran is used in the synthesis of Sch 38516 aglycon (fluvirucin B1) an influenza A antibiotic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Tomita, K. et al.: J. Antibiot., 44, 940 (1991); Houri, A. et al.: J. Am. Chem. Soc., 117, 2943 (1995);

2,5-Dihydrofuran