CAS: 1708092-13-0

7-epi-6beta-Ethyl ursodeoxycholic acid (7EUDCA) is a metabolite of ursodeoxycholic acid. It has been used as a standard for HPLC. 7EUDCA has been found to be an impurity in drug products, and is also used as an analytical reference substance. The chemical formula is C27H46O8 with a molecular weight of 438.737 g/mol and it has been assigned CAS No. 1708092-13-0. 7EUDCA can be synthesized from cholesterol by using the following reaction: A solution of the carboxylic acid (1 eq.), triethylamine (2 eq.), and diethyl malonate (1 eq.) in dry dichloromethane was stirred at room temperature for 18 hours. The solvent was removed under reduced pressure, and the residue was purified by chromatography on silica gel, el