
CAS 170899-08-8: (R)-N-BOC-Allylglycine
Formula:C22H40N2O4
InChI:InChI=1/C12H23N.C10H17NO4/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;1-5-6-7(8(12)13)11-9(14)15-10(2,3)4/h11-13H,1-10H2;5,7H,1,6H2,2-4H3,(H,11,14)(H,12,13)/t;7-/m.1/s1
SMILES:C1CCC(CC1)NC1CCCCC1.C=CC[C@H](C(=O)O)N=C(O)OC(C)(C)C
Synonyms:- Boc-(R)-2-Allylglycine
- (R)-N-tert-Butoxycarbonyl-2-amino-4-pentenoic acid
- (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoate
- (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoic acid-N-cyclohexylcyclohexanamine (1:1)
- Boc-D-Allylglycine.DCHA
- Boc-D-Allylglycine
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Found 5 products.
(R)-N-BOC-Allylglycine, 95%, 98% ee
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C10H16NO4Purity:98%Color and Shape:Clear light yellow, Viscous liquid or pasteMolecular weight:214.244-Pentenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)-
CAS:Formula:C10H17NO4Purity:97%Color and Shape:LiquidMolecular weight:215.2463D-2-Allylglycine, N-BOC protected dicylohexylamine salt
CAS:D-2-Allylglycine, N-BOC protected dicylohexylamine saltPurity:97%Boc-D-Allylglycine
CAS:Purity:98.0%Color and Shape:Liquid, ViscousMolecular weight:215.24899291992188N-Boc-D-allylglycine
CAS:N-Boc-D-allylglycine is a peptidomimetic drug that inhibits caspase-3, an enzyme involved in apoptosis. This drug has been shown to inhibit the proteolytic activity of caspase-3 and thereby inhibit the induction of cell death by various stimuli. N-Boc-D-allylglycine is orally bioavailable and is metabolized into two active analogs: N-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycine (NAGL) and N′-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycinamide (NAG). These active analogs are potent inhibitors of caspase-3, with more than 100 times the potency of the parent compound. This compound also has a prodrug form, which can be hydrolyzed by esterases or glucuronidases to release the active formFormula:C10H17NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:215.25 g/mol