CAS: 171103-04-1

N-Desmethylthiamethoxam is a functional compound that has been synthesized to have similar properties to the neonicotinoids. It is an acetylcholine receptor subtype, which is a neurotransmitter in the central nervous system and peripheral nervous system. N-Desmethylthiamethoxam binds to nitric oxide (NO) and nicotinic acetylcholine receptors (nAChRs), which are the binding sites for acetylcholine. The interaction of N-Desmethylthiamethoxam with these receptors leads to the inhibition of nitrosoguanidine-induced neuronal cell death in vitro. Analytical methods for this product include gas chromatography/mass spectrometry, liquid chromatography/mass spectrometry, and nuclear magnetic resonance spectroscopy. N-Desmethylthiamethoxam is biodegradable and does not accumulate in water or soil environments. The environmental effects of this product are minimal due to its

Applications N-Desmethylthiamethoxam-D4 is an impurity of thiamethoxam and an isotope labelled compound of N-Desmethylthiamethoxam (D292485). Thiamethoxam is a hepatotoxic insecticide in mice. References Swenson, T. L., et al.: Toxicol. Lett., 216, 139 (2013); Karmakar, R., et al.: Pest Manag. Sci, 65, 931 (2009)

Applications N-Desmethylthiamethoxam is an impurity of thiamethoxam. Thiamethoxam is a hepatotoxic insecticide in mice. References Swenson, T. L., et al.: Toxicol. Lett., 216, 139 (2013); Karmakar, R., et al.: Pest Manag. Sci, 65, 931 (2009)