CAS 171722-81-9: Carbamic acid,N-[1,1'-biphenyl]-2-yl-, 1-azabicyclo[2.2.2]oct-4-yl ester, hydrochloride (1:1)

YM-46303 is a potent and selective activator of the human TRPA1 ion channel. It activates TRPA1 in cells expressing this channel by binding to the ligand-binding domain, thereby activating it with high potency. This compound has been shown to inhibit calcium influx in mouse sensory neurons. YM-46303 is a novel, potent, and selective TRPA1 activator that can be used as a research tool for studying the role of this ion channel in physiological responses such as pain sensation.