Folic Acid-D4, with the CAS number 171777-72-3, is a deuterated form of folic acid, which is a water-soluble B-vitamin (B9) essential for various biological functions, including DNA synthesis and repair, amino acid metabolism, and the production of red blood cells. The deuteration indicates that certain hydrogen atoms in the folic acid molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the substance's utility in research, particularly in studies involving metabolic pathways and tracer studies in biological systems. Folic Acid-D4 retains the core structure and biological activity of folic acid, making it relevant in nutritional studies and potential therapeutic applications. It is typically used in scientific research rather than as a dietary supplement. As with other forms of folic acid, it is important to handle it with care in laboratory settings, following appropriate safety protocols.

Folic Acid-D4

171777-72-3: N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl-2,3,5,6-d4]-L- glutamic Aci, (N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl-2,3,5,6-d4]-L-), N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl-2,3,5,6-d4]-L-glutamic Acid

Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.
References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),


CAS 171777-72-3: Folic Acid-D4

Folic Acid-d4

Ref: TR-F680302

Folic Acid-d4

Ref: 4Z-F-242