4-Pregnene-11B,17A,20A,21-tetrol-3-one, with the CAS number 1719-79-5, is a steroid compound that belongs to the class of pregnanes, which are characterized by a steroid backbone with a specific arrangement of functional groups. This compound features multiple hydroxyl (-OH) groups, indicating it has significant alcohol functionality, which can influence its solubility and reactivity. The presence of a ketone group (3-one) suggests it may participate in various chemical reactions typical of ketones, such as nucleophilic additions. The stereochemistry of the compound, indicated by the specific designations (B, A), plays a crucial role in its biological activity and interaction with steroid receptors. Steroids like this one are often involved in various physiological processes, including hormonal regulation. Its structural complexity and functional groups may also suggest potential applications in medicinal chemistry or biochemistry, particularly in the study of steroid metabolism or the development of therapeutic agents. However, specific biological activities and pharmacological properties would require further investigation.

4-pregnene-11B,17A,20A,21-tetrol-3-one

1719-79-5: (11Beta)-11,17,20,21-Tetrahydroxypregn-4-En-3-One

20-α-Dihydro Cortisol

Applications 20α-Dihydrocortisol is a metabolite of Cortisol (H714615) which is a topical corticosteroid (1), more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis (3); suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References Clark, D. et al.: Steroids 7, 352 (2006)


CAS 1719-79-5: 4-pregnene-11B,17A,20A,21-tetrol-3-one

20-α-Dihydro Cortisol

Ref: 4Z-C-2751

20alpha-Dihydrocortisol

Ref: TR-D459580

20-α-Dihydro Hydrocortisone

Ref: 4Z-H-103042