![(3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F394515-3as-233a-4-tetrahydro-1h-pyrrolo-21-c-124-benzothiadiazine-55-dioxide.webp&w=3840&q=75)
CAS 175340-20-2: (3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide
Formula:C10H12N2O2S
InChI:InChI=1S/C10H12N2O2S/c13-15(14)9-5-2-1-4-8(9)12-7-3-6-10(12)11-15/h1-2,4-5,10-11H,3,6-7H2/t10-/m1/s1
InChI key:InChIKey=MNTIJYGEITVWHU-SNVBAGLBSA-N
SMILES:O=S1(=O)C=2C(N3[C@@](N1)(CCC3)[H])=CC=CC2
Synonyms:- S 18986
- S 18986-1
- 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (S)-
- (3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide
- 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aS)-
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S 18986
CAS:S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties inFormula:C10H12N2O2SPurity:99.25%Color and Shape:SolidMolecular weight:224.28S 18986
CAS:S 18986 is a novel molecule that binds to the glutamate receptor. It has been shown to protect neurons against glutamate-induced cell death in vitro and in vivo, as well as reversing memory deficits in aged mice. S 18986 also increases the production of neurotrophic factors and enhances neuronal function. The pharmacokinetics of S 18986 have been studied using a population modeling approach. This approach provides an asymmetric synthesis route for the preparation of this compound. S 18986 has also been shown to increase locomotor activity, which may be due to its ability to potentiate GABAergic transmission.END>Formula:C10H12N2O2SPurity:Min. 95%Molecular weight:224.28 g/mol
