CAS 17615-73-5: 5-Amino-2-[(4-aminophenyl)sulfonyl]benzenesulfonamide

Sulfamoyldapsone is a synthetic antimicrobial compound, which is derived from the dapsone family. Its source is primarily synthetic, designed through chemical modifications of the parent compound dapsone, a well-known antibacterial agent. The mode of action of sulfamoyldapsone involves the inhibition of bacterial folic acid synthesis. By targeting dihydropteroate synthase, an enzyme essential for the production of folic acid in microorganisms, the compound effectively interferes with bacterial growth and replication. The primary applications of sulfamoyldapsone are in the treatment of leprosy and as a component in multidrug regimens for this chronic infectious disease. It may also have potential uses in other antimicrobial therapies, though these are less established. Researchers continually explore its efficacy and safety profile in various clinical and experimental settings to better understand its full spectrum of activity and potential therapeutic benefits.