CAS 17700-09-3: 2,3,4-Trichloronitrobenzene

1,2,3-Trichloro-4-nitrobenzene

2,3,4-Trichloronitrobenzene is a synthetic chemical that can be found in the environment as a result of human activity. 2,3,4-Trichloronitrobenzene is used for the production of other chemicals and is also used as an intermediate in the synthesis of herbicides and pesticides. Chronic lymphocytic leukemia (CLL) is a type of cancer that forms in white blood cells called lymphocytes. It has been shown that 2,3,4-trichloronitrobenzene is one of many carcinogens that cause CLL. The mechanism by which it causes cancer may involve the nitrosation of phenylacetonitrile to form N-nitrosodiphenylamine (NDEA). This process occurs when 2,3,4-trichloronitrobenzene reacts with sodium carbonate and phenylacetonitrile to form sodium nitrite and

Applications 2,3,4-Trichloronitrobenzene is a useful synthetic intermediate that is mainly used as the starting material in the synthesis of third generation quinolone antibacterial drugs, such as Lomefloxacin (L469415, HCl) and Ofloxacin (O245750). 2,3,4-Trichloronitrobenzene is also used as the starting material in the synthesis of Aclonifen (A190200); a compound used as a pesticide and herbicide. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lu, Y., et al.: Guangdong Huagong, 36, 20 (2009); Laini, A., et al.: Sci. Total Environ., 438, 312 (2012); Fantke, P., et al.: Enviorn. Int., 49, 9 (2012)