CAS 17720-18-2: Pyridinium, 3-carboxy-1-β-D-ribofuranosyl-, inner salt

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1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)Pyridin-1-Ium-3-Carboxylate

Applications The labelled analogue of an effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells. References Yang, T. et al.: J. Med. Chem., 50, 6458 (2007);

Nicotinic acid riboside is a nicotinic acid derivative that has been shown to increase NAD+ levels in cells. Nicotinic acid riboside has been shown to increase the activity of enzymes involved in energy metabolism and transfer reactions, as well as target enzymes such as nicotinamide phosphoribosyltransferase (NAMPT) and its substrate, nicotinamide mononucleotide (NMN). It also increases cellular NAD+ levels by inhibiting the degradative enzyme, nicotinamide phosphoribosyltransferase (NAMPT). Nicotinic acid riboside can be used to treat metabolic disorders such as diabetes mellitus type 2.

Nicotinic acid riboside is a natural product for research related to life sciences. The catalog number is T67407 and the CAS number is 17720-18-2.

Applications An effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells. References Yang, T. et al.: J. Med. Chem., 50, 6458 (2007);