CAS 17745-04-9: Imidazo[1,2-a]pyridine-3-acetic acid

2-(Imidazo[1,2-a]pyridin-3-yl)acetic acid

Imidazo[1,2-a]pyridin-3-yl-acetic acid is a drug that belongs to the class of HIV protease inhibitors. It is a potent inhibitor of the human proprotein convertase subtilisin/kexin type 9 (PCSK9) enzyme. Imidazo[1,2-a]pyridin-3-yl-acetic acid has been shown to inhibit PCSK9 activity in postprandial plasma and hepatic lipase in vitro. PCSK9 inhibition leads to an increase in high density lipoprotein cholesterol (HDL) levels, which may be beneficial for patients with atherosclerotic cardiovascular disease. Imidazo[1,2-a]pyridin-3-yl-acetic acid also has antiatherogenic properties through its ability to lower triglycerides and free fatty acids. The reaction solution used for this experiment was hydrochloric acid (HCl