CAS 1776-09-6: 4H-1-Benzopyran-4-one, 3-bromo-2,3-dihydro-

3-Bromo-2,3-dihydro-4H-chromen-4-one

3-Bromo-2,3-dihydro-4H-chromen-4-one is a borohydride reduction and molecular modeling study of an analog of the natural product. The 14α-demethylase enzyme catalyzes the conversion of 3β,14α-dihydroxyandrostane to 3β,14β-dihydroxyandrostane. This enzyme has stereoselective activity in the synthesis of androgens from progesterone. The hydrogen bond interactions between the active site residues and solvent molecules are important for the enzymatic activity.