CAS 1782-79-2: 4-Cyclopentene-1,3-dione,4,5-dimethoxy-2- [(2E)-1-oxo-3-phenyl-2-propenyl]-

Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line.

Linderone is a small molecule that belongs to the group of natural products. It has been shown to have significant cytotoxicity against human cancer cells in vitro and in vivo, as well as anti-inflammatory activity. Linderone has also been found to be neuroprotective in an animal model of HIV infection and is known to suppress the transcriptional regulation of genes involved in immune responses. The mechanism of action for linderone is not yet fully understood, but may involve its ability to activate deuterium isotopes. Linderone has also been shown to inhibit fatty acid synthesis and induce apoptosis in skin cells, which may contribute to its effects on cancer and ischemia reperfusion.