CAS: 178451-13-3

Applications Raloxifene 6-Monoomethyl Ether, is an impurity of Raloxifene (R100000), which is A nonsteroidal, selective estrogen receptor modulator (SERM). It is used in the prevention of osteoporosis in postmenopausal women. References Jone, C.D., et al.: J. Med. Chem., 27, 1057 (1984), Buelke-Sam, J., et al.: Reprod. Toxicol., 12, 217 (1998),

Compound 7, Raloxifene 6-Monomethyl Ether, blocks estrogen receptor α, inhibits MCF-7 cells; IC50=250 nM, pIC50=6.6.