CAS: 1784751-20-7

CK1-IN-1 is a research tool that can be used to study the function of ion channels and receptors. This compound is a ligand that binds to cell surface receptors and activates them, thereby initiating biological responses. CK1-IN-1 also inhibits the activity of protein kinase C (PKC) by binding to PKC and preventing it from phosphorylating its substrates. It has been shown to inhibit the activity of various ion channels, including sodium channels, potassium channels, calcium channels, and chloride channels. The inhibition of these ion channels leads to an increase in the membrane potential, which can lead to epileptic seizures. This compound is highly pure with a purity level greater than 99%.

CK1-IN-1

CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.