Fmoc-D-Dap(Alloc)-OH, with the CAS number 178924-05-5, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of Dap (Diaminopropionic acid) and features a fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is widely utilized to protect amino groups during peptide synthesis. The presence of the Alloc (allyloxycarbonyl) group provides additional functionality, allowing for selective deprotection under specific conditions, which is advantageous in the synthesis of complex peptides. This compound is typically characterized by its solid state at room temperature and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its structure includes both amine and carboxylic acid functional groups, making it reactive in various chemical reactions. Fmoc-D-Dap(Alloc)-OH is particularly valuable in the field of medicinal chemistry and biochemistry for the development of peptide-based therapeutics and for studying protein interactions. Proper handling and storage conditions are essential to maintain its stability and reactivity.

Fmoc-D-Dap(Alloc)-OH

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(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(((allyloxy)carbonyl)amino)propanoic acid

D-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(2-propen-1-yloxy)carbonyl]amino]-

Fmoc-D-Dap(Alloc)-OH is a synthetic compound that inhibits bacterial growth. It binds to the lipase active site and prevents hydrolysis of substrates such as c1-6 alkyl, phenoxy, and coumarin derivatives. Fmoc-D-Dap(Alloc)-OH is also an analog of Daptomycin. Fmoc-D-Dap(Alloc)-OH has been shown to inhibit the growth of human cancer cells by inhibiting the activity of cytotoxic heterocyclic amines, which are a class of chemicals that can cause DNA damage. The compound has also been shown to inhibit oxytocin receptor function in vitro, which may be due to its ability to bind with this receptor on the cell surface.

CAS 178924-05-5: Fmoc-D-Dap(Alloc)-OH

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(((allyloxy)carbonyl)amino)propanoic acid

Ref: 10-F547069

D-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(2-propen-1-yloxy)carbonyl]amino]-

Ref: IN-DA0026HW

Fmoc-D-Dap(Alloc)-OH

Ref: 3D-FF72506

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(((allyloxy)carbonyl)amino)propanoic acid

Ref: 54-OR76055