2-Aminopurine CEP, with the CAS number 178925-41-2, is a synthetic analog of adenine, a purine nucleobase. This compound is characterized by the presence of an amino group at the 2-position of the purine ring, which influences its biological activity and interaction with nucleic acids. It is often used in molecular biology and biochemistry as a mutagen and as a tool for studying DNA replication and repair mechanisms. 2-Aminopurine can incorporate into DNA and RNA, potentially leading to mispairing during replication, which can result in mutations. The compound is typically soluble in water and organic solvents, making it versatile for various experimental applications. Additionally, it exhibits properties that allow it to act as a competitive inhibitor of certain enzymes involved in nucleotide metabolism. Its use in research is significant for understanding genetic processes and the effects of mutagens on cellular functions. However, safety precautions should be taken when handling this compound due to its potential biological effects.

2-AMINOPURINE CEP

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Applications 2-Aminopurine(N2-Dmf) 2'-Deoxy-riboside CE Phosphoramidite shows fluorescent properties of oligonucleotides.
References Seio, Kohji. et al., Bioorg. Med. Chem. 21,3197-3201(2013);


2-Aminopurine(N2-Dmf) 2'-Deoxy-riboside CE Phosphoramidite

Methanimidamide, N'-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-9H-purin-2-yl]-N,N-dimethyl-

N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a novel, modified nucleoside analog with antiviral and anticancer properties. It is synthesized by the reaction of 2′,5′-O-(4,4′-dimethoxytrityl)-9-(2′deoxy-5′-O-DMT b D ribofuranosyl)purine 3′ with a phosphoramidite reagent in DMF at elevated temperature. The compound has been shown to inhibit viral replication in vitro and in vivo. In addition to its antiviral activity, N2DMFP3'-CE also inhibits tumor cell growth.

CAS 178925-41-2: 2-AMINOPURINE CEP

2-Aminopurine(N2-Dmf) 2'-Deoxy-riboside CE Phosphoramidite

Ref: TR-A357830

Methanimidamide, N'-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-9H-purin-2-yl]-N,N-dimethyl-

Ref: IN-DA0026HV

N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite

Ref: 3D-PD09020

N2-DMF-9-(2''-deoxy-5''-O-DMT-b-D-ribofuranosyl)purine 3''-CE phosphoramidite

Ref: 7W-GN6756