![Ethyl 7,7a-dihydro-7-(hydroxyimino)benzo[b]cyclopropa[e]pyran-1a(1H)-carboxylate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F311985-ethyl-77a-dihydro-7-hydroxyimino-benzo-b-cyclopropa-e-pyran-1a-1h-carboxylate.webp&w=3840&q=75)
CAS 179067-99-3: Ethyl 7,7a-dihydro-7-(hydroxyimino)benzo[b]cyclopropa[e]pyran-1a(1H)-carboxylate
Formula:C13H13NO4
InChI:InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,16H,2,7H2,1H3
InChI key:InChIKey=FXCTZFMSAHZQTR-UHFFFAOYSA-N
SMILES:C(OCC)(=O)C12C(C1)C(=NO)C=3C(O2)=CC=CC3
Synonyms:- 7-(Hydroxyimino)Cyclopropa[B]Chromen-1A-Carboxylate Ethyl Ester
- 7-Hydroxyiminocyclopropan[B]Chromen-1A-Carboxylic Acid Ethyl Ester
- Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxylic acid, 7,7a-dihydro-7-(hydroxyimino)-, ethyl ester
- Ethyl 7,7a-dihydro-7-(hydroxyimino)benzo[b]cyclopropa[e]pyran-1a(1H)-carboxylate
- ethyl (7E)-7-(hydroxyimino)-7,7a-dihydrocyclopropa[b]chromene-1a(1H)-carboxylate
- CHEMBL327783
- CPCCOEt
- CHEMBL 327783
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Found 4 products.
CPCCOEt
CAS:CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1bFormula:C13H13NO4Purity:99.87%Color and Shape:SolidMolecular weight:247.25Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxylic acid, 7,7a-dihydro-7-(hydroxyimino)-, ethyl ester
CAS:Formula:C13H13NO4Purity:98%Color and Shape:SolidMolecular weight:247.2466CPCCOEt
CAS:CPCCOEt is a glutamate receptor antagonist that binds to the metabotropic glutamate receptor subtype 2 (mGluR2) and blocks its activation. CPCCOEt has been shown to inhibit the death of neurons, axonal growth, and neuronal sprouting in vitro. It also prevents the neurotoxicity induced by glutamate or NMDA in cultured cortical neurons and microdialysis probes. CPCCOEt prevents the opening of voltage-dependent calcium channels, which leads to a decrease in cytosolic Ca2+ levels. This inhibition results in an increase in neuronal survival and protection against excitotoxic injury. CPCCOEt has been shown to have a protective effect on brain damage caused by stroke or cerebral ischemia in animal models.Formula:C13H13NO4Purity:Min. 95%Molecular weight:247.25 g/mol
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