CAS 179324-69-7: Bortezomib
Formula:C19H25BN4O4
InChI:InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
InChI key:InChIKey=GXJABQQUPOEUTA-RDJZCZTQSA-N
SMILES:[C@H](CC1=CC=CC=C1)(C(N[C@@H](CC(C)C)B(O)O)=O)NC(=O)C=2C=NC=CN2
Synonyms:- B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
- Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
- Boronic acid, [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-
- Boronic acid, [3-methyl-1-[[1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-, [S-(R*,S*)]-
- Bortezomib for research
- Bortizomib
- Brotezamide
- Dpba
- Ldp 341
- Mg 341
- Mln 341
- See more synonyms
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Found 12 products.
Bortezomib
CAS:Controlled ProductStability Hygroscopic and Moisture Sensitive Applications Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);Formula:C19H25BN4O4Color and Shape:White To Off-WhiteMolecular weight:384.24Bortezomib - Bio-X ™
CAS:Bortezomib is a selective and reversible inhibitor of the multicatalytic 26S proteasome. The inhibition of protein breakdown affects several metabolic pathways and leads to cell death. The compound is effective in treating t-cell lymphomas and multiple myeloma because it prevents the binding of myeloma cells to bone marrow stroma and inhibits osteoclast differentiation. Bortezomib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C19H25BN4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:384.24 g/molBortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:100% - 99.97%Color and Shape:Yellow SolidMolecular weight:384.24Ref: TM-T2399
5mg52.00€10mg64.00€25mg80.00€50mg96.00€100mg144.00€200mg225.00€500mg373.00€1mL*10mM (DMSO)52.00€Bortezomib, 98%
CAS:A potent, highly selective and reversible inhibitor of the 20S proteasome, Bortezomib is used as an antineoplastic agent, which controls the growth of cancer cells. It is also useful in the treatment of multiple myeloma. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H25BN4O4Purity:98%Color and Shape:White to off-white, Powder or crystals or crystalline powderMolecular weight:384.24Bortezomib
CAS:BortezomibFormula:C19H25BN4O4Purity:98% (nmr) (Typical Value in Batch COA)Color and Shape: white solidMolecular weight:384.24g/molBortezomib
CAS:Formula:C19H25BN4O4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:384.24Bortezomib-D8 (Major)
CAS:Controlled ProductApplications Labelled Bortezomib, which the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells.d6-3%d7-10%d8-86% Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005)Formula:C19H17D8BN4O4Color and Shape:Off-WhiteMolecular weight:392.29Bortezomib
CAS:Formula:C19H25BN4O4Purity:≥ 98.0%Color and Shape:White to off-white powder or solidMolecular weight:384.24Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
CAS:Formula:C19H25BN4O4Purity:98%Color and Shape:SolidMolecular weight:384.2372Bortezomib
CAS:Selective and reversible inhibitor of the multicatalytic 26S proteasome. The inhibition of protein breakdown affects several metabolic pathways and leads to cell death. The compound is effective in treating multiple myeloma because it prevents the binding of myeloma cells to bone marrow stroma and inhibits osteoclast differentiation.Formula:C19H25BN4O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:384.24 g/mol
![Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0026XG.jpg&w=3840&q=75)
