The chemical substance known as Urea, N-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-, with the CAS number 179343-17-0, is a complex organic compound characterized by its unique structural features. It contains a urea functional group, which is indicative of its potential applications in pharmaceuticals and agrochemicals. The presence of a pyrido[2,3-d]pyrimidine moiety suggests that it may exhibit biological activity, possibly as an inhibitor or modulator of specific enzymes or receptors. The dichlorophenyl group contributes to its lipophilicity, potentially enhancing its ability to penetrate biological membranes. Additionally, the presence of a tert-butyl group may influence its solubility and stability. Overall, this compound's intricate structure implies that it could be of interest in medicinal chemistry, particularly in the development of targeted therapies or as a research tool in biochemical studies. However, specific properties such as solubility, melting point, and biological activity would require empirical investigation for comprehensive characterization.

Urea,N-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-

PD-089828

PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).

PD 089828

Pd 089828 is a compound that inhibits the proliferation of cancer cells. It binds to receptors involved in the growth and metastasis of cancer cells, thereby inhibiting the binding of growth factors to their receptor. Pd 089828 has been shown to inhibit epidermal growth factor, which is a potent mitogen that stimulates cell division and inhibits apoptosis. This drug also has anticancer activity against breast cancer by blocking epidermal growth factor-induced cellular proliferation. It also shows anticancer activity in muscle cells by preventing muscle cell proliferation.

CAS 179343-17-0: Urea,N-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-

PD-089828

Ref: 54-BUP03924

PD-089828

Ref: TM-T8976

PD 089828

Ref: TR-P217440

Pd 089828

Ref: 3D-EHA34317