CAS: 179464-23-4

Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.

Terrestrosin D is a natural antibiotic, which is derived from specific strains of soil-dwelling bacteria. These bacteria belong to the Streptomyces genus, renowned for their prolific production of bioactive compounds with antimicrobial properties. The mode of action of Terrestrosin D involves the inhibition of protein synthesis by binding to the bacterial ribosome, thereby obstructing the translation process and effectively stalling bacterial growth. This mechanism targets both Gram-positive and certain Gram-negative bacteria, granting it a broad-spectrum efficacy. The primary applications of Terrestrosin D are in the field of microbiology and pharmaceutical research, where it is utilized for studying bacterial protein synthesis pathways and exploring new therapeutic avenues for bacterial infections. Additionally, it serves as a tool for understanding resistance mechanisms and helps in the development of novel antibiotics by providing a structural and functional framework that supports the design of derivative compounds.